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Diabetes Control in Dialysis-Dependent Kidney Failure

The purpose of this study is to learn if a study medication called semaglutide (known as Ozempic) improves blood sugar control in people treated with dialysis.

Age & Gender

  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide), Texas

What will be asked of you

If you enroll in the study, you will be randomized to receive semaglutide or placebo (dummy drug). The study is double-blinded, which means neither you nor the researchers will know which you are on. You have a 50% chance of receiving the active drug, semaglutide. Once you are randomized, the study involves taking a shot of the medication every week and monitoring your blood sugars. We will give you all the supplies you need for this study. At certain times during the study, you will wear a continuous glucose monitor, which is a small device that you can wear on your arm or your belly and reads your blood sugar every 5 minutes. The visits will often be by phone, but you will need to come into clinic at least four times during the study.

Incentives

Up to $480 dollars, Blood sugar monitoring devices, comprehensive diabetes care

In-person visits:
4-6
Phone or online visits:
10-12
Total length of participation:
1 year 2 months

Looking for Specific Volunteers

Able to participate:

  • You have type 2 diabetes
  • You have dialysis-dependent kidney failure

Not eligible if:

  • You have type 1 diabetes
  • You are not treated with dialysis

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Klara Klein
Medicine-Endocrinology

Study Type

Clinical or Medical
Interventional

Study Topics

Chronic Conditions
Diabetes
Kidneys and Liver
Obesity

IRB Number

23-1060

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