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Peanut Allergy Study for Children and Adolescents

The purpose of this clinical study is to learn more about the safety and effectiveness of an experimental drug for the treatment of peanut allergy (PVX108) in children aged 4 to 11 years and adolescents (aged 12 to 17 years) with peanut allergy. We want to compare dose levels of the study drug in children aged 4 to 11 years. We want to see if the study drug is safe and reduces peanut allergy in younger children.

Age & Gender

  • 4 years ~ 11 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

-Physical exam and vital signs -Blood and urine sample collection -Allergy skin testing -Oral Food Challenge Test -Injection of study medication monthly -Phone calls after the injection days to check on child

Incentives

Information provided upon request, Parking Vouchers

In-person visits:
18-20
Phone or online visits:
10-12
Total length of participation:
Approximately 18 months

Looking for Specific Volunteers

Able to participate:

  • You have a peanut allergy

Not eligible if:

  • Receiving any type of allergy immunotherapy
  • Poorly controlled asthma
  • Participation in other clinical trials

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Edwin Kim
Pediatrics - Allergy Immunology and Rheumatology

Study Type

Clinical or Medical
Interventional

Study Topics

Allergy

IRB Number

23-2178

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