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Study on fatty acid supplement for GI upset during radiation therapy

In this study, we want to learn more about the effect of investigational Short-chain fatty acids (SCFA) on quality of life and treatment-related side effects during radiation therapy.

Age & Gender

18 years ~ 99 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)
Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

If you decide to take part in this study, you will frequently meet with a member of the study team in addition to your oncology care team. You will receive either a SCFA oral supplement or a placebo (inactive supplement) before starting radiation therapy. You will complete diaries about taking the supplement and how you are feeling, and we will run some tests.

In-person visits:
7-10

Phone or online visits:
1-2

Total length of participation:
72 months

Looking for Specific Volunteers

Able to participate:

You are 18 years old or older
You plan to have radiation therapy for a cancer located in the abdomen or pelvic area
(Prior chemotherapy or surgery is allowed)

Not eligible if:

You have a history of inflammatory bowel disease or GI motility disorder; history of Congestive heart failure
You have had abdominopelvic radiation treatment
You are on a salt restricted diet for medical reasons
You are pregnant or breastfeeding
You have a severe nut allergy

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Shivani Sud
Radiation Oncology

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Breast, Colorectal, Cervical, Prostate, Stomach and Esophageal, Uterine (endometrial), Ovarian)
Stomach, Digestion and Gut Health

IRB Number

20-0257

ClinicalTrials.gov

NCT04700527

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Questions?

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