The purpose of this study is to test the safety of the two study drugs, venetoclax and selinexor, and to find the highest dose of venetoclax and selinexor that can be given safely when it is combined with chemotherapy drugs (cytarabine or cytarabine and fludarabine). This study tests different doses of venetoclax and selinexor to see which dose is safer in children with leukemia.
Thank you for your interest, but this study is recruiting by invitation only.
United States (Nationwide)
Thomas Alexander
Pediatrics - Hematology/Oncology
Clinical or Medical
Interventional
Cancer (Pediatric Cancers, Leukemia)
Child and Teen Health
22-0392