Open

Myelofibrosis Treatment Study

The purpose of this study is to learn more about the safety and effectiveness of the study drug (INCB057643) as monotherapy for participants with relapsed or refractory myelofibrosis.

Age & Gender

18 years ~ 99 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

This study aims to treat your cancer and closely resembles routine care that would be received regardless of participating on a research study. To participate on the study, you will frequently meet with a member of the study team in addition to your oncology care team. The study requires you to have fresh tissue biopsies at least two times and CT scans once every three months during your participation. The study involves blood collection for research purposes in addition to routine blood work as well as frequent EKG's and Echo's to monitor your heart function.

Incentives

gas reimbursement up to 25 miles; hotels and meals up to $200; parking reimbursement

In-person visits:
8+

Total length of participation:
9 months

Looking for Specific Volunteers

Able to participate:

You are at least 18 years old
You are not pregnant or trying to become pregnant, or breastfeeding
You have a new diagnosis of Myelofibrosis or Other relapsed Advanced Myeloid Neoplasms including those that did not respond to a previous treatment.

Not eligible if:

You have severe complications of Leukemia
You have used another treatment in the last 14 -28 days
You have had a bone marrow transplant in the last three to six months
You have a history of a bleeding disorder for example a previous GI bleed. _

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Lineberger Clinical Trials Office
cancerclinicaltrials@med.unc.edu
(919) 966-4432

Primary Visit Location

Lineberger Comprehensive Cancer Center
NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Brandi Reeves
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Leukemia)

IRB Number

20-1212

ClinicalTrials.gov

NCT04279847

Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH. This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

Helpful Links

Questions?

This email address is being protected from spambots. You need JavaScript enabled to view it.