Cohort for Pediatric Translational and Clinical Research in IBD (CAPTURE IBD)

1. To create a prospective cohort of pediatric IBD patients with active disease initiating or changing medical, dietary, or surgical therapy. 2. Identify unique subgroups of pediatric patients with high likelihood of response/non-response to specific therapies through integrated analysis of demographic, clinical, and multi-omic molecular data. 3. Define surgical, clinical, and endoscopic outcomes of ileal surgery for pediatric Crohn's disease and clinical and molecular predictors of post-operative endoscopic disease recurrence.