Wood smoke pollution is a common problem across the world, including in the US. This wood smoke comes from people using wood to heat and cook, as well as from wildfires. The purpose of this research study is to screen individuals to see how they respond to wood smoke inhalation by measuring cells in sputum (or phlegm, that you cough up) to see if there is an increase in the number of cells after exposure. The exposure will be to 500ug/m3 of WSP for 2 hours, with intermittent exercise on a bicycle and rest. The wood is burned in a typical wood stove and piped into the chamber. There is a specific gene that we believe impacts the response to wood smoke exposure, we will also look to see if you have this gene or not (about 40% -60% of people do).
During your 3 visits, you will have a total of 4 blood draws and 3 sputum inductions. The full participation day involves exposure to wood smoke for a total of 2 hours with 15 minutes of exercise on a stationary bike and 15 minutes of rest.
$400 Visa gift card
Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.
Center for Environmenal Medicine, Asthma and Lung Biology (CEMALB)
U.S. EPA Human Studies Facility (UNC-Chapel Hill)
104 Mason Farm Rd, Chapel Hill, NC 27514, USA
David Peden
Pediatrics - Allergy Immunology and Rheumatology
Clinical or Medical
Interventional
Healthy Volunteer or General Population
Lungs and Breathing
15-1775
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