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Chronic Lymphocytic Leukemia Study

The purpose of this study is to collect more information about how effective a combination of medications are in treating CLL in people who have not received previous treatment for their cancer.

Age & Gender

  • 18 years ~ 99 years
  • Male, Female

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

The study drug obinutuzumab will be given as an IV infusion (through a vein in your arm). The second study drug, venetoclax, will be take by mouth at home. Study visits will include blood draws, bone marrow biopsies and/or aspirations and stool samples. We will also do CT scans or MRIs of your chest, pelvis, abdomen, and any other areas of your body that your study doctor thinks are appropriate so that we can look at and measure your disease.

Incentives

study medication

In-person visits:
24-33
Total length of participation:
up to 5 years

Looking for Specific Volunteers

Able to participate:

  • You have previously untreated chronic lymphocytic leukemia (CLL)
  • You have You have good blood and blood cell function for those diagnosed with CLL blood and blood cell function for those diagnosed with chronicYou
  • You have good kidney and liver function

Not eligible if:

  • You have had prior chronic lymphocytic leukemia (CLL) directed therapy.
  • You require the use of warfarin
  • You have a history of liver disease, including active viral or other hepatitis, current alcohol abuse, or cirrhosis
  • You have had a history of certain types of cancers

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Christopher Jensen
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Leukemia)

IRB Number

21-0031

ClinicalTrials.gov

NCT04447768

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