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Polycythemia Vera Study

This research study is for people with Polycythemia Vera (PV) who need to start therapy to reduce blood counts or whose current therapy is not controlling their PV. In this study we want to find out if a new drug can help normalize your blood count.

Age & Gender

  • 18 years ~ 99 years
  • Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

If you decide to take part, you will receive investigational medication in the form of a shot every two weeks. At each visit you will be asked questions about your health and the medications you're taking. You will also answer questionnaires. Blood draws for routine tests should be expected at every onsite visit. The study team will will perform an ultrasound to measure the size of your spleen, an eye exam, a chest X-ray, an Echocardiogram (ECHO) of your heart and a possible bone marrow biopsy at screening. You have the option to take part in an optional bone marrow biopsy and optional genetic through your participation in the study.

Incentives

$75 stipend for each completed visit., study medication, gas reimbursement as applicable, lodging reimbursement as applicable.

In-person visits:
27+
Phone or online visits:
10+
Total length of participation:
48 weeks with a one month follow up

Looking for Specific Volunteers

Able to participate:

  • You have been diagnosed with polycythemia vera (PV).
  • You have good kidney and liver function

Not eligible if:

  • You have taken a medication that decreased your blood cell count
  • You have an autoimmune disease or compromised lung function
  • Use of any research medication within 4 weeks of the first dose of medication with this study.
  • You have poorly controlled diabetes.
  • You have a history of alcohol or drug abuse

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Brandi Reeves
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Leukemia)

IRB Number

23-1736

ClinicalTrials.gov

NCT05481151

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