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Early Stage Breast Cancer Study (CAMERAN)

The aim of this study is to learn more about the quality of life and cancer outcomes in low-risk elderly breast cancer patients. Participants in this study will be randomly assigned to either accelerated partial breast irradiation or endocrine therapy. Both treatment options have been widely used.

Age & Gender

  • 65 years ~ 99 years
  • Female

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

Patients will be asked to complete up to 3 sets of questionnaires. The study consists of 2 different treatments. Group 1 will be randomly assigned to receive accelerated partial breast irradiation (APBI) alone. This will include radiation delivered every other day to location of your lumpectomy. Group 2 will receive endocrine therapy for 5 years or more.

Incentives

Information provided upon request

In-person visits:
Along with normal clinic visits
Phone or online visits:
00
Total length of participation:
2 years

Looking for Specific Volunteers

Able to participate:

  • You are 65 years with de novo invasive carcinoma of breast

Not eligible if:

  • You will have pre- or post-operative systemic chemotherapy while in this study.
  • You are currently undergoing treatment with anti-hormonal agents
  • You are on hormonal replacement therapy
  • You have a multicentric tumor

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Lineberger Comprehensive Cancer Center
NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Dana Casey
Radiation Oncology - Chapel Hill

Study Type

Clinical or Medical
Observational

Study Topics

Cancer (Breast)

IRB Number

21-2251

ClinicalTrials.gov

NCT05472792

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