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How do APOE genetic variants impact brain metabolism?

The purpose of this research study is to measure the effect of a genetic variation in the APOE gene and obesity on how sugar enters and is used by the human brain.

Age & Gender

30 years ~ 55 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

Each participant in this study will receive a concentrated sugary drink, a glucose infusion, an MRI scan, and bloodwork.

Incentives

up to $275

In-person visits:
3

Phone or online visits:
1 pre-screening call

Total length of participation:
Approximately 3 months

Looking for Specific Volunteers

Able to participate:

You are non-diabetic and have normal weight
you are non-diabetic and overweight/obese

Not eligible if:

You are pregnant, trying to become pregnant, or are breastfeeding
You have claustrophobia
You have a pacemaker or some metal objects inside your body

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

Biomedical Research Imaging Center
Marsico Hall (UNC-Chapel Hill)
125 Mason Farm Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Janice Hwang
Medicine-Endocrinology

Study Type

Clinical or Medical
Interventional

Study Topics

Brain, Head, Nervous System
Eating, Nutrition, and Metabolism
Healthy Volunteer or General Population
Obesity

IRB Number

23-0632

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Questions?

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