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How do APOE genetic variants impact brain metabolism?

The purpose of this research study is to measure the effect of a genetic variation in the APOE gene and obesity on how sugar enters and is used by the human brain.

Age & Gender

  • 30 years ~ 55 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)


North Carolina (Statewide)

What will be asked of you

Each participant in this study will receive a concentrated sugary drink, a glucose infusion, an MRI scan, and bloodwork.


up to $275

In-person visits:
Phone or online visits:
1 pre-screening call
Total length of participation:
Approximately 3 months

Looking for Specific Volunteers

Able to participate:

  • You are non-diabetic and have normal weight
  • you are non-diabetic and overweight/obese

Not eligible if:

  • You are pregnant, trying to become pregnant, or are breastfeeding
  • You have claustrophobia
  • You have a pacemaker or some metal objects inside your body

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

Biomedical Research Imaging Center
Marsico Hall (UNC-Chapel Hill)
125 Mason Farm Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Janice Hwang

Study Type

Clinical or Medical

Study Topics

Brain, Head, Nervous System
Eating, Nutrition, and Metabolism
Healthy Volunteer or General Population

IRB Number


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