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Team Science Protein Supplement Pilot Study

We are conducting a study to evaluate patterns of specific blood proteins that may explain differences in how β-hydroxy-methyl-butyrate (HMB), a protein supplement acts in older adults with weakness. When we use the term weakness, we refer to changes that occur with aging that result in decreased muscle strength, slow walking speeds, exhaustion, and decreased handgrip strength.

Age & Gender

  • 65 years ~ 85 years
  • Male, Female

Visit Availability

  • Standard business hours (M-F, 8-5)


North Carolina (Statewide)

What will be asked of you

During these visits, we'll conduct a range of tests and questionnaires designed to understand your physical function and overall health better. These include physical function tests to assess your strength, simple questionnaires to gather information about your daily activities and any changes you might notice, and blood and stool collections to analyze how your body responds to the HMB supplement. In addition, we'll provide you with state-of-the-art MRI and ultrasound scans to get a closer look at your muscle function. These tests are painless and non-invasive, and our team will guide you through every step of the process.


Total length of participation:
3 months

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

  • UNC Patient
  • 65 to 85 years of age
  • Multiple Chronic Conditions
  • Subjective Weakness

Not eligible if:

  • Currently taking weight loss promoting medications
  • Dementia
  • Life-threatening conditions
  • Elective Surgery in the next 4 months
  • Unable to perform study procedures

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Biomedical Research Imaging Center
Marsico Hall (UNC-Chapel Hill)
125 Mason Farm Rd, Chapel Hill, NC 27514, USA

Secondary Visit Location

UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

John Batsis
Med-Geriatric Medicine

Study Type

Clinical or Medical

Study Topics

Bones, Joints, Muscles
Eating, Nutrition, and Metabolism

IRB Number




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