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IgA Nephropathy Microbiome Study

The purpose of this study is to compare diet (record of the foods you eat), gut microbiome (stool sample), and cells (blood sample) in adults with IgA Nephropathy (IgAN) and compare with adults with focal segmental glomerulosclerosis (FSGS) and adults with no history of medical problems. The information we learn by doing this study may help us understand how we might be able to target the microbiome to better understand the disease process and potentially help us develop new therapies in the future.

Age & Gender

  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Visits can be combined with regular clinical appointments


New York, North Carolina (Statewide)

What will be asked of you

Participants will need to provide a blood sample in the clinic, a stool (poop) sample collected at home and shipped to UNC, and answer a dietary questionnaire before and after they give the stool sample.


$30 for completion of the enrollment visit, $20 for each completed dietary survey, and $50 for completion of the stool sample, for a maximum of $100 total.

In-person visits:
Phone or online visits:
Total length of participation:
2 in-person visits, 2 phone visits over 1-2 months.

Looking for Specific Volunteers

Able to participate:

  • IgA Nephropathy
  • FSGS
  • Healthy Controls

Not eligible if:

  • Do not have IgA Nephropathy
  • Do not have FSGS
  • Do not want to collect a stool sample

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

  • You do not have a health history except for obstructive sleep apnea, bronchial asthma on bronchodilators, and hypertension controlled on medications

Not eligible if:

  • You do not want to get your blood drawn
  • You do not want to collect a stool sample

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Visit Study Website

Primary Visit Location

UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Secondary Contact

Secondary Visit Location

Columbia University Irving Medical Center
622 W 168th St, New York, NY 10032, USA

Additional Study Information

Principal Investigator

Manish Saha

Study Type

Clinical or Medical

Study Topics

Healthy Volunteer or General Population
Kidneys and Liver

IRB Number


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