Characterizing Multi-omic Postoperative Crohn's Disease (ChaMP)

The study is designed to look at Crohn's disease over a period time, from before a surgery to 12 months after the surgery has taken place. The role bacteria in the gut plays in Crohn's disease (CD) is not well understood. Which particular microbes contribute to disease remain unknown. In CD, ~70% of patients will end up requiring surgery due to chronic unrelenting complications, and ~50% require additional surgery. We hope to identify key microbes at the time of surgery in stool and tissue and correlate it over time with data collected at timepoints after surgery. We will use this data with clinical information to determine if specific microbes are associated with disease recurrence.