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Relapsed or Refractory Leukemia Study

This is a research study for people diagnosed with Leukemia that has returned after being in remission. The purpose of this study is to see if the study medication (LP-118) works better in treating your cancer.

Age & Gender

  • 18 years ~ 99 years
  • Male, Female

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

If you decide to take part, you will be given the medication LP-118 that is tablet to be taken once daily. At each visit you will be asked questions about your health and any other medications you're taking. Blood draws for routine tests should be expected at every onsite visit. A study team member will assess the effect of your cancer on how well you perform activities of daily living. you will be asked to complete a pill diary as directed, including recording the date and time when you take the medication. Bone Marrow biopsies are required through out the study at different time points. CT/MRI/PETCT scan are required at least 4 times while participating in the study.

Incentives

Study Medication, Gas Reimbursement as applicable, meal reimburement as applicable, lodging reimbursement as applicable.

In-person visits:
36+
Total length of participation:
3+ years

Looking for Specific Volunteers

Able to participate:

  • You have test results that show your form of Leukemia cancer has returned.
  • You have good kidney and liver function

Not eligible if:

  • You have had a stem cell transplant recently
  • You have taken certain medications to treat your Leukemia.
  • You have heart disease
  • You currently have another type of cancer that is also being treated.

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Joshua Zeidner
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Leukemia)

IRB Number

21-0759

ClinicalTrials.gov

NCT04771572

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