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Mother and Infant Determinants of Vascular Aging Study (MIDAS)

The purpose of this research study is to estimate the future cardiovascular disease risk in pregnant women and their infants. We will use questionnaires, maternal and infant central pulse wave velocity (PWV) which is a measure of arterial stiffness (vascular aging) that predicts cardiovascular disease. This non-invasive instrument is totally safe in pregnancy. By measuring the time it takes for blood leaving your heart to reach your leg with the use of 2 small cuffs, it is able to determine arterial stiffness which is a key component of cardiovascular disease.

Age & Gender

  • 18 years ~ 45 years
  • Female

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

At each visit, the study staff will measure your pulse wave velocity, draw a small amount of blood, email you some questionnaires regarding lifestyle, sleep behaviors, diet and well-being for you to do at home. Once your baby has been born, we will also measure his/her pulse wave velocity. At delivery, we will collect a small amount of cord blood and a segment of placenta. There will be an optional infant blood draw at the 6 and 12 month follow-up visits.

Incentives

Up to $350 for completion of all study visits and questionnaires

In-person visits:
3
Phone or online visits:
3
Total length of participation:
16 months

Looking for Specific Volunteers

Able to participate:

  • You are pregnant with a single baby and in the third trimester
  • You have no Hypertension, diabetes OR you DO have hypertension or gestational diabetes

Not eligible if:

  • You have participated in this study in a prior pregnancy
  • You are pregnant with more than one baby
  • You will not deliver at UNC Women's Hospital
  • You are leaving the area within 12 months of your baby's delivery

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Fetzer Hall (UNC-Chapel Hill)
210 South Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Michelle Meyer
Center for Womens Health Research

Study Type

Clinical or Medical
Observational

Study Topics

Pregnancy

IRB Number

21-2131

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