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A PHASE Ib/II, OPEN-LABEL, MULTICENTER, RANDOMIZED UMBRELLA STUDY EVALUATING THE EFFICACY AND SAFETY OF MULTIPLE TREATMENT COMBINATIONS IN PATIENTS WITH LOCALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK (MORPHEUS-HEAD AND NECK CANCER)

This is a Phase Ib/II, open-label, multicenter, randomized, umbrella study in patients with locally advanced SCCHN. The study will enroll treatment-naive patients with resectable Stage III-IVA HPV-negative, PD-L1 positive SCCHN with measurable disease.

Age & Gender

  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive

Contact the Team

Location

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North Carolina (Statewide)

Additional Study Information

Principal Investigator

Shetal Patel
Lineberger Comprehensive Cancer Center

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Head and Neck)

IRB Number

22-2886

ClinicalTrials.gov

NCT05459129

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