The GET IT RIgHT Study

The reasons this study is being conducted are: • To see if human immunodeficiency virus (HIV) antiretroviral medicines that you are taking continue to work well in transgender women and other individuals identifying as female or transfeminine but with male sex assigned at birth (referred to as transgender women throughout this form) when taken with feminizing hormone therapy (FHT), also known in this study as estradiol; and • To see if estradiol levels in blood vary between boosted and un-boosted HIV medicines when transgender women are taking different doses of FHT.