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2779 studies match your search
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Study of BGB-A425 in Combination With Tislelizumab in Advanced Solid Tumors

Do you have histologically or cytologically documented locally advanced or recurrent non-small cell lung cancer (NSCLC) that is not eligible for curative surgery and/or definitive radiotherapy with or without chemoradiotherapy, or metastatic-nonsquamous or squamous NSCLC? If so, you may be eligble to participate in a research study investigating the safety, tolerability, pharmacokinetics and preliminary antitumor activity of various combinations of investigational drugs (BGB A425 and LBL-007) with Tislelizumab.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck, Lung)
Not currently enrolling

A Feasibility Study to Assess Drone Delivery of Automated External Defibrillators (AEDs)

The purpose of this study is to assess the feasibility of drone delivery of an Automated External Defibrillator (AED) for a simulated cardiac arrest.

Age & Gender
  • 18 years ~ 65 years
  • Male, Female
Study Interest
  • Heart and Circulation
  • Healthy Volunteer or General Population
Visit Location
Not currently enrolling

FIT Study

The purpose of this research study is to compare three different FDA approved treatments for fecal incontinence (also known as accidental bowel leakage) in men and women in terms of how well the treatments work, how safe the treatments are, and now much the treatments cost. Patients would undergo Enhanced Medical Management (EMM) for 1 month to optimize bowel function, as we have found EMM controls leakage symptoms in many individuals. Those who do not experience >75% reduction in leakage episodes would then be randomized into biofeedback, SNS, or dextranomer. Patients are followed for two years.The treatments are biofeedback therapy, sacral nerve electrical stimulation (SNS), or dextranomer injections.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
  • Women's Health
  • Men's Health
Open

Study of ATLCAR.CD138 cells for relapsed/refractory Multiple Myeloma

Have you been diagnosed with Relapsed/Refractory Multiple Myeloma? You may be able to take part in a gene transfer research study that uses your own modified immune cells to see if it is effective in treating your cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)
Open

Study of CAR-T cells in relapsed/refractory Hodgkin's Lymphoma and Cutaneous T-Cell Lymphoma

Do you have Hodgkin's Lymphoma, or Cutaneous T-Cell Lymphoma? Has your lymphoma come back, or did not get better after your last treatment? If so, you might be able to take part in a study that will modify your own immune cells to see if it may treat your lymphoma.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)
Not currently enrolling

Hearing study - 60 to 85 year-old adults with normal hearing

The purpose of our research is to obtain a better understanding of hearing. During the course of the study, you will sit in a soundproof booth and listen to sounds presented over headphones. When a target sound is heard, you will be prompted to make a response by pressing a button on a response box.

Age & Gender
  • 5 years ~ 85 years
  • Male, Female
Study Interest
  • Aging
  • Ear, Nose, and Throat
  • Healthy Volunteer or General Population

Study of RGX-202-01 w/ or w/o FOLFIRI in Patients with Advanced Colorectal Cancer

To evaluate the safety and efficacy of RGX-202-01 alone and in combination with 5-fluorouracil and leucovorin plus irinotecan

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Colorectal, Pancreatic, Stomach and Esophageal, Other Cancers)
Not currently enrolling

19F MRI Healthy vs. CF

Researchers are collecting data on lung imaging to evaluate how well a person's lungs are working which will provide additional information about lung disease and how such diseases respond to treatment. The purpose of this study is to evaluate the use of inert (non-reactive) gas mixed with oxygen as contrast agent to image the airway spaces in normal human lungs and the lungs of persons with cystic fibrosis. A contrast agent helps the investigator to see spaces inside your lungs that are normally not visible. These images will be compared with spirometry (a non-imaging measure of global lung function used routinely in the clinic).

Age & Gender
  • 18 years ~ 99 years
  • Male
Study Interest
  • Healthy Volunteer or General Population
  • Lungs and Breathing
Open

Registry for Adults With Plasma Cell Disorders.

Have you been diagnosed with a plasma cell disorder? You may be able to join a registry to help us learn more about the effects of plasma cell disorders on different aspects of life.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Multiple Myeloma)
Open

Ulixertinib/Palbociclib in Patients With Advanced Melanoma

Have you been diagnosed with melanoma? If so, you may be eligible to take part in a research study looking at the safety of giving a combination of drugs called Ulixertinib and Palbociclib to patients with advanced melanoma.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Melanoma)
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