In this research study, we want to learn more about the V940 (mRNA-4157) vaccine given in combination with pembrolizumab (V940 plus pembro) in people who have surgery to remove their melanoma. This trial will compare V940 plus pembro given after surgery to a placebo plus pembrolizumab given after surgery.

Have you been diagnosed with high-risk Melanoma skin cancer? Are you now melanoma free after surgery? If so, you may be able to take part in this research study. This study will compare a new combination of drug (Fianlimab and cemiplimab) with another standard drug (pembrolizumab). This will allow the study team to understand the side effects of the treatment, how they work and if they improve the quality of life.

Did you play sports in high school or college? You may be eligible to participate in this research study aimed at understanding sport-related concussion care. Help us understand more about sport-related concussion care behaviors by completing this survey!

Have you been diagnosed with Platinum-Resistant Ovarian Carcinoma, Endometrial Adenocarcinoma, or Urothelial Carcinoma? If so, you may be able to take part in a research study utilizing prexasertib as Monotherapy and in Combination with Gemcitabine.

Do you wonder about your mobility as you age? You may be eligible to participate in a research study investigating age effects on foot-ankle interactions with carbon fiber insoles. The goal of this study is to enhance foot and ankle function in aging and mobility. Compensation provided.

The study involves research of three study drugs, given alone or in combination. The combination of the study drugs is referred to as T-Plex. The purpose of the study is to learn if the study drugs are well tolerated and effective in treating your type of cancer.

If you have Testosterone-driven Salivary Gland Cancer, you may be able to participate in a research study testing the anti-cancer drug Darolutamide.

Do you have a cancer that is advanced or metastatic? Has your cancer progressed on one or more standard of care therapies? If you answered yes, then this research study may be for you. Study drug will be provided. 8

Have you been diagnosed with Prostate, Bladder, or Kidney Cancer? If so, you may be able to take part in a research study investigating the optimal way to combine or sequence therapies in patients with Rare Genitourinary Tumors.

The purpose of this study is to test good and bad effects of different drugs against metastatic brain tumors with altered genes. This trial is trying to see if tumor genetic testing would be helpful at guiding treatment in patients such as you. Researchers have looked at the DNA material (genes) that can be affected in brain metastases and have found several genes that are altered, or mutated. There are medications that target these genes. We are doing this study because we want to find out if this approach is better or worse than the usual approach for your metastatic cancer. The usual approach is defined as care most people get for your metastatic cancer.