This study allows for the collection of a large volume of stem cells via Leukapheresis from healthy HIV negative donors. These stem cells are then aliquoted and frozen for use by the Garcia Lab in the production of HIV negative (delta 32 negative) humanized mice.

The goal of this project is to revise an observer impression scale to assess the peer social competence of preschool children, examine the reliability and validity of the scale and its usability for teachers in early learning programs in the U.S.

The goal of this study is to explore differences in the content and structure of patient care across and within pediatric endocrinology centers. This mixed-methods study will describe clinic level demographics and processes across several international pediatric endocrinology clinics, as well as explore the roles and approach to delivering diabetes education and support. Results from this study will increase understanding of what may be driving disparate patient outcomes across centers and support future quality improvement research.

The purpose of this research study is to learn more about what marijuana users' think of the of current marijuana warnings on the packages and to get their feedback on newly developed marijuana warnings. Participants will be recruited to participate in a one-time online focus group discussion. The total study duration will be 60-90 minutes. During the focus group participates will be asked about their understanding of the risks of using marijuana products and provide their reaction to current and improved marijuana warnings.

To establish the recommended Phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for 5 consecutive days.

The purpose of this study is to understand the explanations teachers provide for elementary and middle grades students' mathematical success and struggle ("attributions of mathematical excellence") using interviews.

Our study will survey 7,500 adults ages 18-59 who identify as alcohol drinkers. We aim to assess participant sources of alcohol, their drinking behavior, and associated harms before, during, and late in the COVID-19 pandemic. We will be recruiting participants from five different states so we can look at differences across a variety of state alcohol policy environments.

The purpose of this study is to create a biorepository of blood samples form patients with myasthenia gravis that may be used with collaborators in the development of new therapeutics for myasthenia gravis (MG).

This project will explore the potential implications of polygenic scores for social traits by surveying biobank members and interviewing scientists who develop or could use polygenic scores for social traits.

In partnership with the NC Injury and Violence Prevention branch, the UNC Injury Prevention Research Center has been facilitating a peer learning network initiative for harm reduction practitioners in the central Appalachian region for the past 3 years. This initiative, the "Sharing Harm Reduction Practices (SHARP) Network," is funded by the CDC's Overdose Data to Action program and is entering the final project year. We are conducting a process evaluation of the network to document 1) the ways in which the network has supported practitioners in their work and 2) how we built the network in case other regions would like to replicate our efforts. We plan to conduct 8 qualitative interviews with peer members to understand their experience as network participants.