To examine the personal significance or clinical concerns among different individuals associated with having various gastrointestinal symptoms, as reflected in self-reported bothersomeness, life interference and potential for needing medical attention for those symptoms. Also to evaluate associated factors such as the symptom-related quality of life effects and impact on psychological wellbeing.

To demonstrate efficacy of Bexsero in prevention of urogenital and/or anorectal gonococcal infection. To estimate efficacy of Bexsero in prevention of overall gonococcal infection and by anatomical site (urogenital, anorectal or pharyngeal). To assess safety of Bexsero.

We want to assess If the abnormal network patterns seen in seizure networks of epilepsy have similar implications when observed in patients with severe acute brain injury and therefore are modulated by antiseizure medication (ASM). If those networks respond to the ASM, then they may have a relationship with epileptogenic brain activity in this clinical context too and therefore could benefit from ASM even though they do not present ictal activity on their EEG.

The purpose of this study is to conduct an exploratory learning needs assessment for implementation science stakeholders in low- and middle-income countries that could provide customized training for different stakeholders.

This study is a randomized pilot trial that will assess the possibility of further Vitamin K trials. In this study we will compare the effects of 1000 micrograms per day of Vitamin K vs. a placebo on circulating blood proteins. Additionally, we will use participation data to estimate recruitment and retention rates, differences between research locations, and response rates to questionnaires for a large scale clinical trial.

Researchers from the University of North Carolina at Chapel Hill are seeking input from community members interested in joining a Community Advisory Board (CAB) with a focus on improving knowledge around the impacts of extreme weather-related disasters and healthcare access. The purpose of this CAB is to ensure the proposed research remains relevant and useful to the broader community in all phases of research - from forming partnerships to using research results to inform policy and advocacy actions.

The purpose of this study is to learn more about the experiences of families with children who have peanut or other food allergies. It also explores parents' (or other caregivers') and adolescents' perceptions of available food allergy treatments, as well as clinical research options.

The purpose of this study is to assess the effect of emotional support groups and educational webinars on the well-being of patients with rare dermatologic conditions characterized by blistering. Patients will be given a survey before and after participating in six support group and webinar meetings.

To initiate and evaluate a multilevel navigation intervention to promote lung cancer screening among Black/African Americans

To improve adolescent health by leveraging teachers to provide mental health care for adolescents with poor access to care in Darjeeling, India