The purpose of this study is two-fold: 1) Determine if inexpensive force-sensing shoe insoles can be reliably used for feedback interventions to improve walking in individuals after anterior cruciate ligament reconstruction (ACLR). 2) Determine if quadriceps strength associates with the ability to modify change walking patterns in individuals with a history of anterior cruciate ligament reconstruction (ACLR).

The purpose of this study is to identify barriers and facilitators to the implementation of integrative medical group visits (IMGV) for patients with chronic pain in safety-net healthcare settings. IMGV is one of few integrative pain management programs designed specifically for low-income populations. By understanding what it takes to make these programs successful or not, we aim to test strategies to implement IMGV widely in safety-net settings. The goal is to make integrative pain management more accessible to low-income patients.

The study tests the safety and efficacy of a new type of drug, administered by intravenous infusion, for the treatment of lupus nephritis or IgA Nephropathy. You might be on the drug or on the placebo (no active drug ) and will help to figure out if this new drug is a good alternative or complement to existing drugs.

The purpose of this study is to conduct interviews to hear people's thoughts and feedback on various aspects of conducting syphilis vaccine research at UNC-Chapel Hill and to ask them to complete a brief online survey after their interviews. The information that participants provide will help the clinical trial researchers to better understand what concerns people might have about syphilis vaccine research and to design clinical trials that are acceptable to potential vaccine research participants.

The IBIS Network recently received a grant from NIH to study brain and behavior development in infants with Down Syndrome as well as non affected infants. The goal of our new study is to identify the features of Down Syndrome at an earlier age. We will be recruiting infants across all IBIS Network locations 6-months of age and younger. Travel and Compensation provided.

Have you been recently diagnosed with Diffuse Large B Cell Lymphoma? Are you over 75 years of age? If so, you may be able to take part in a research study looking at the safety of giving a new study drug CC-486 (oral azacitidine) in addition to the standard chemotherapy drug combination used to treat this disease.

The study involves an interview about preferences in health tracking devices, followed by performing a handful of actions with a companion app to one of these devices. Finally, there are a few questions about the experience of using the app. This is being done to learn more about the preferences and expectations of people who may use such devices and whether those expectations are being met.

The IBIS Network recently received a $9.5 million grant from NIH to replicate our previous study of brain and behavior development in infants at risk for developing autism. The goal of our new study is to identify the symptoms of autism at an earlier age. We will be recruiting 250 infants across all IBIS Network locations 6-months of age and younger from families we have not previously seen. All infants we see will have at least one full older, full sibling diagnosed with autism spectrum disorder.

We are conducting a research study of UNC community members' preferences for ideas to enhance safety and wellbeing among UNC community members during the COVID-19 pandemic. The purpose of this study is to help researchers understand which strategies the UNC community would prefer to see implemented as the 2020-2021 school year proceeds.

Asthma education is very important for patients with asthma to manage their disease. In this study, we are testing an asthma education website to learn if it can improve asthma knowledge.