Leveraging our decades of experience studying the acute and chronic effects of traumatic brain injury (TBI) and concussion, our investigative team propose an innovative, translational approach that bridges both preclinical and clinical studies. We propose testing multiple potential preventative and therapeutic strategies in the preclinical setting, while simultaneously conducting a prospective, longitudinal study of neurologic health outcomes associated with concussion and sub-concussive exposure in former NFL players. Our prior studies of former NFL players over the past 15 years provide us with a unique opportunity to conduct a truly prospective, longitudinal study of long-term neurologic health outcomes and determine any possible association with concussion and repetitive sub-concussive exposure. In parallel, we have developed animal models of repeated concussions (repetitive mild TBI [rmTBI]) and chronic traumatic encephalopathy (CTE). We have studied the effects of readily translatable preventative and therapeutic strategies, including the N-methyl-D-aspartate (NMDA) receptor antagonist memantine, low dose carbon monoxide
In this study, we want to learn more about the experiences and activities of high school-aged youth after a neurological event. This study will also help us to understand the perspectives of youth and a parent/caregiver through photos and stories.
This study is being done to see if the study drug, called BI 764198, may help people with a type of kidney disease called focal segmental glomerulosclerosis (abbreviated FSGS). Researchers are trying to figure out if the study drug can reduce the amount of protein in your urine, also known as "proteinuria".
This study aims to assess the efficacy and safety of Tezepelumab injections as a treatment for EoE.
Do you have a solid tumor? Would you like to have screening done to see if you are eligible for a treatment study? If so, you may be able to take part in a study that will look at your tumor sample to see if you are eligible for another investigational treatment study.
Have you been diagnosed with Low Risk Breast Cancer? Have you already been treated with surgery? If so, you may be able to take part in a research study looking at the effect of regional nodal radiotherapy.
Learn more about the learning experiences of undergraduate students when they take Asian Studies courses in order to improve the engagement of students in the future.
Are you a healthy female? If you are between 18-30 years old, may be able take part in a study to learn more about fatigue due to exercise! Please contact us if you are interested in learning more. Compensation provided.
Have you had ACL reconstruction in the past 1-3 years? You may be able to take part in a research study to help us learn more about how the type of shoes you wear influences your walking mechanics.
Nowadays, AI systems have been applied widely in a variety of predictive tasks, from objective detection to text classification. These AI systems have greatly advanced automated decision-making. However, sometimes humans and AI systems think in very different ways, which means humans and AI systems might use different evidence to make predictions. In this study, we are using sentiment analysis of Amazon product reviews as a case study. Humans will judge sentiments of different words with different AI explanations. Human and AI judgments will be compared to find to which extend human and AI knowledge align.