Do you have severe sickle cell disease? If so, you may be eligible to participate in a research study that is looking at the safety and effectiveness of using your own modified stem cells as possible treatment.

Are you a trained male runner interested in how to get an edge on the competition? A group of researchers in the EXSS department is investigating the benefit of carbon fiber-plated running shoes on running economy (efficiency). All participants will receive personal VO2max, gait analysis and kinematic data upon completion of the study. Participants must have run an 18:00 5k (males) or 21:00 5K (females), or a comparable performance in another distance event in the past year.

Does your child have frequently relapsing or steroid dependent nephrotic syndrome? This study is testing a medicine called obinutuzumab, and comparing it with another one, mycophenolate mofetil (MMF), to see which works better for children with nephrotic syndrome.

Do you have Alpha-1 antitrypsin deficiency?

Have you been infected with COVID-19? Are you a solid organ transplant recipient? Have you or your child received a COVID-19 vaccine or are planning to receive one? If so, you may be eligible to participate in a research study that will assess your immune response to COVID-19 infection or vaccination over a 5 year period. We are looking for children and adults aged 7-95 years, and plan to collect blood every 2-6 months over the study period. (Compensation provided for the first year).

Do you sit too much at work or home? There is strong evidence for an association between sitting and cardiovascular diseases such as coronary heart disease and stroke. In this study, we want to identify strategies to break up sitting for long periods of time. Compensation will be provided.

Do you have depression? We are doing a study to learn more about a new form of non-invasive brain stimulation. We want to learn if individualized brain stimulation that matches your brain waves can improve depression symptoms. This is an open-label study and every eligible participant receives this experimental treatment. Compensation is provided.

Are you between the ages of 40 and 60? Participate in a study exploring the perceptions of health messages and how we can promote healthier lifestyles for people of all backgrounds. Compensation provided.

Are you pregnant? If you are in your 3rd trimester, you may be able to take part in a research study. In this study, we want to learn more about how different kinds of exercise can help reduce risk for high blood pressure in pregnancy and other possible pregnancy complications.

Do you or did you have COVID-19 while pregnant? We are doing a study to better understand the long-term effects of COVID-19 and who is at greatest risk of having long-term effects. Pregnant women with COVID-19 or women who had COVID-19 during their pregnancy or postpartum period with the last 24 months are invited to enroll.